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Powerful Punch Providing Relief

For over 20 years, ZYMOX® Dermatology and Oratene Brushless Oral Care® products have been recommended by veterinarians to provide relief for the most common health conditions that affect pets. While common, these conditions can be very costly, frustrating to the pet parent to manage and painful to the pet.

At the center of all ZYMOX and Oratene® products is the advanced technology of the patented LP3 Enzyme System. These enzymes are found naturally in milk, are 100% safe and gentle, and each has its own unique properties. When combined, they pack a powerful antimicrobial punch. This combination of enzymes work synergistically to promote healthy skin, ears, and mouths.

ZYMOX Dermatology Retail Line

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RZAESH1201
ZYMOX Advanced Enzymatic Shampoo - 12 oz

Average rating of 0 out of 5 stars

ZYMOX® Advanced Enzymatic Shampoo is formulated to soothe, hydrate, and relieve sensitive, extremely dry, itchy, or irritated skin of pets of any age with gentle, hypoallergenic and pH balanced ingredients.  Features the antimicrobial patented LP3 Enzyme System, a concentrated combination of naturally derived enzymes, plus hydrating Vitamin D3 and Avena sativa (oat) extract to calm, nourish, and care for the skin.  Does not contain parabens or detergents.Made in the USAUsesItchy allergy skinIrritated or Inflamed skinGentle cleansingHealthy skin supportFeaturesGentleSoothingNourishingNo sting, non-irritatingWon’t strip the coatTear-freePleasant smellingNo harsh ingredientsNo detergents, chlorines, or parabensSafe for all animalsAvailable Sizes: 12 oz and Gallon
$16.50*
RZAEC1201
ZYMOX Advanced Enzymatic Conditioner - 12 oz

Average rating of 0 out of 5 stars

ZYMOX® Advanced Enzymatic Conditioner is formulated to soothe, hydrate, and relieve sensitive, extremely dry, itchy, or irritated skin of pets of any age with gentle, hypoallergenic and pH balanced ingredients. Can be used three ways: lightly rinsed off, used as a leave-on, or applied full-strength as a cream to problematic areas. Does not contain silicone or parabens. Dries non-greasy.Made in the USA.Uses Itchy allergy skinIrritated or inflamed skinConditioningDetanglingMoisturizingHealthy skin supportFeaturesSoothingPleasant smellingDries non-greasyLeave on or rinse offNon-toxic, worry-free if lickedNo silicones or parabensNo harsh ingredientsAvailable Sizes: 12 oz and GallonRelief for Itchy Skin Due to Allergies and Other Troublesome Skin ProblemsZYMOX dermatology products for skin provide relief by employing the potent, patented LP3 Enzyme System. They provide natural enzyme-based alternatives to manage complications of allergies and other skin-related issues.
$16.50*
RZSH1200
ZYMOX Shampoo, Authentic Product Made in the USA - 12 oz

Average rating of 0 out of 5 stars

Supports skin and coat health by helping wash away build-up of dirt, debris and pollen. Formulated with the patented LP3 Enzyme System which blends a concentrated combination of protein, enzymes and Vitamin D3 to be safe and gentle on all pets of all ages. ZYMOX® Shampoo uses mild, non-drying ingredients that is soothing to the skin; is pH-balanced, tear-free and paraben free.  Features a pleasant fragrance.Made in the USA.UsesItchy allergy skinIrritated or Inflamed skinGentle cleansingHealthy skin supportFeaturesGentleSoothingNourishingNo sting, non-irritatingWon’t strip the coatTear-freePleasant smellingNo harsh ingredientsNo detergents, chlorines, or parabensSafe for all animalsAvailable Sizes: 12 oz and GallonRelief for Itchy Skin Due to Allergies and Other Troublesome Skin ProblemsZYMOX dermatology products for skin provide relief by employing the potent, patented LP3 Enzyme System. They provide natural enzyme-based alternatives to manage complications of allergies and other skin-related issues.
$17.59*
RZRI1200
ZYMOX Leave-On Conditioner, Authentic Product Made in the USA - 12 oz

Average rating of 0 out of 5 stars

Provides skin soothing conditioning of the coat and skin formulated with the patented LP3 Enzyme System which blends a combination of protein, enzymes and Vitamin D3.  ZYMOX® Leave-On Conditioner is safe and gentle for all pets of all ages. Moisturizes and detangles. May be rinsed off, left on or applied full strength to areas needing extra attention. Features a pleasant fragrance. Non-greasy. Non-toxic.Does not contain silicone or parabens.Made in the USA.UsesItchy allergy skinIrritated or inflamed skinConditioningDetanglingMoisturizingHealthy skin supportFeaturesSoothingPleasant smellingDries non-greasyLeave on or rinse offNon-toxic, worry-free if lickedNo silicones or parabensNo harsh ingredientsAvailable Sizes: 12 oz and GallonRelief for Itchy Skin Due to Allergies and Other Troublesome Skin ProblemsZYMOX dermatology products for skin provide relief by employing the potent, patented LP3 Enzyme System.Our leave in conditioner provides natural enzyme-based alternatives to manage complications of allergies and other skin-related issues. Contact us to learn more.
$16.78*
RZTS0200W
ZYMOX Topical Spray with 0.5% Hydrocortisone, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

Promotes healthy skin and provides relief from itching caused by inflammation, dermatitis, and other minor skin irritations.  ZYMOX® Topical Spray features the patented LP3 Enzyme System which blends a concentrated combination of protein and enzymes plus skin soothing aloe vera and 0.5% hydrocortisone for itch relief.  The Spray is ideal for areas away from the face.Made in the USA.UsesItch reliefDermatitisSkin irritationsPromotes healthy skinOn the body or pawsFeaturesNo stingNon-irritatingNon-toxicWorry-free if lickedNo harsh ingredientsNo parabens, chlorhexidine, benzalkonium chloride, antibiotics, alcoholOnly requires application 1 – 2 times per dayAvailable Size:  2 ozRelief for Itchy Skin Due to Allergies and Other Troublesome Skin ProblemsZYMOX dermatology products for skin provide relief by employing the potent, patented LP3 Enzyme System. They provide natural enzyme-based alternatives to manage complications of allergies and other skin-related issues.
$18.69*
RZTC0100W
ZYMOX Topical Cream with 0.5% Hydrocortisone

Average rating of 0 out of 5 stars

This cream promotes healthy skin and provides relief from itching caused by inflammation, dermatitis, and other minor skin irritations.  ZYMOX® Topical Creams contains the patented LP3 Enzyme System which blends a concentrated combination of protein, enzymes plus skin soothing aloe vera and 0.5% hydrocortisone for itch relief. The Cream features a catheter tip for direct application. Ideal for areas around the face, paws, and body folds.Made in the USA.UsesItch reliefDermatitisSkin irritationsPromotes healthy skinOn the body, face, paws, body foldsFeaturesSoothingNo stingNon-irritatingNon-toxicWorry-free if lickedCatheter tip for direct applicationNo harsh ingredientsNo parabens, chlorhexidine, benzalkonium chloride, antibiotics, alcoholOnly requires application 1 – 2 times per dayAvailable Size:  1 ozRelief for Itchy Skin Due to Allergies and Other Troublesome Skin ProblemsZYMOX dermatology products for skin provide relief by employing the potent, patented LP3 Enzyme System. They provide natural enzyme-based alternatives to manage complications of allergies and other skin-related issues. Contact us today to learn more.
$17.16*
RZFTC0100
ZYMOX Enzymatic Topical Cream with 0.5% Hydrocortisone for Cats & Kittens, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

ZYMOX® Enzymatic Topical Cream with 0.5% Hydrocortisone for Cats and Kittens promotes healthy skin and provides relief from itching and hot spots caused by inflammation, dermatitis, skin allergies, insect bites and other minor skin irritations. Veterinarian recommended and endorsed by TICA, The International Cat Association.  ZYMOX® Enzymatic Topical Cream contains a combination of enzymes plus skin-soothing aloe vera and zinc gluconate and 0.5% hydrocortisone for itch relief. The Cream features a catheter tip for direct application.  Ideal for areas around the face, paws, and body folds.This product contains 0.5% hydrocortisone and is not for use on pregnant or lactating females.Made in the USA.UsesItch reliefDermatitisSkin irritationsInsect bitesFeline acnePromotes healthy skinOn the body, face, paws, body foldsFeaturesSoothingNo stingNon-irritatingNon-toxicWorry-free if lickedCatheter tip for direct applicationNo harsh ingredientsNo parabens, chlorhexidine, benzalkonium chloride, antibiotics, alcoholOnly requires application 1 – 2 times per dayAvailable Size:  1 oz
$17.59*

ZYMOX Dermatology Veterinary Line

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ZYTSWO
ZYMOX Topical Spray w/out Hydrocortisone, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

Highly effective in the management of wounds, cuts, abrasions and skin infections due to bacteria, fungus or yeast, without the use of antibiotics.  ZYMOX® Topical Spray features the patented LP3 Enzyme System which blends a concentrated combination of protein and enzymes plus skin-soothing aloe vera.  No disinfection is needed of the site prior to application.  Available with and without hydrocortisoneHydrocortisone Free for those animals sensitive to corticosteroids such as pregnant or lactating females, rabbits and exotics.This hydrocortisone free formulation is recommended for those animals sensitive to corticosteroids such as pregnant or lactating females, rabbits and exotics.The ZYMOX  Topical Spray is available with and without hydrocortisone.Made in the USA.UsesWounds, cuts, abrasionsSkin infectionsDermatitisMoist pyoderma/hot spotsPromotes healthy skinOn the body, away from faceItch relief with 1% hydrocortisoneFeaturesNo stingNon-irritatingNon-toxicWorry-free if lickedNo harsh ingredientsNo parabens, chlorhexidine, benzalkonium chloride, antibiotics, alcoholOnly requires application 1 – 2 times per dayAvailable Size:  2 ozRelief for Itchy Skin Due to Allergies and Other Troublesome Skin ProblemsZYMOX dermatology products for skin provide relief by employing the potent, patented LP3 Enzyme System. They provide natural enzyme-based alternatives to manage complications of allergies and other skin-related issues.
$17.59*
ZYTS
ZYMOX Topical Spray w/1% Hydrocortisone, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

Promotes healthy skin and provides relief from itching caused by inflammation, dermatitis, and other minor skin irritations. ZYMOX® Topical Spray features the patented LP3 Enzyme System which blends a concentrated combination of protein and enzymes plus skin-soothing aloe vera and 1.0% hydrocortisone for itch relief. This anti-itch spray for dogs, cats, and other pets is ideal for areas away from the face.This formulation with added 1% hydrocortisone is for animals that are not sensitive to hydrocortisone for additional itch relief.The ZYMOX  Topical Spray is available with and without hydrocortisone.Made in the USA.UsesItch reliefDermatitisSkin irritationsPromotes healthy skinOn the body or pawsFeaturesNo stingNon-irritatingNon-toxicWorry-free if lickedNo harsh ingredientsNo parabens, chlorhexidine, benzalkonium chloride, antibiotics, alcoholOnly requires application 1 – 2 times per dayAvailable Size:  2 ozRelief for Itchy Skin Due to Allergies and Other Troublesome Skin ProblemsZYMOX® dermatology products for skin provide relief by employing the potent, patented LP3 Enzyme System. They provide natural enzyme-based alternatives to manage complications of allergies and other skin-related issues.Have Questions? Click here to contact us.
$19.79*
ZYTCWO
ZYMOX Topical Cream w/out Hydrocortisone, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

Highly effective in the management of wounds, cuts, abrasions and skin infections due to bacteria, fungus or yeast, without the use of antibiotics.  ZYMOX® Topical Cream features the patented LP3 Enzyme System which blends a concentrated combination of protein and enzymes plus skin-soothing aloe vera.  No disinfection is needed of the site prior to application.  Available with and without hydrocortisone.This hydrocortisone free formulation is recommended for those animals sensitive to corticosteroids such as pregnant or lactating females, rabbits and exotics.The ZYMOX Topical Cream is available with and without hydrocortisone.Made in the USA.UsesWounds, cuts, abrasionsDermatitisPromotes healthy skinOn the body, face, paws, body foldsItch relief with 1% hydrocortisoneFeaturesNo stingNon-irritatingNon-toxicCatheter tip for direct applicationWorry-free if lickedNo harsh ingredientsNo parabens, chlorhexidine, benzalkonium chloride, antibiotics, alcoholOnly requires application 1 – 2 times per dayAvailable Size:  1 ozRelief for Itchy Skin Due to Allergies and Other Troublesome Skin ProblemsZYMOX dermatology products for skin provide relief by employing the potent, patented LP3 Enzyme System. They provide natural enzyme-based alternatives to manage complications of allergies and other skin-related pet issues. Contact us to learn more.
$17.59*
ZYTC
ZYMOX Topical Cream With 1% Hydrocortisone, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

Highly effective in the management of wounds, cuts, abrasions and skin infections due to bacteria, fungus or yeast, without the use of antibiotics.  ZYMOX® Topical Cream features the patented LP3 Enzyme System which blends a concentrated combination of protein and enzymes plus skin-soothing aloe vera.  No disinfection is needed of the site prior to application.  Available with and without hydrocortisoneThis formulation with added 1% hydrocortisone is for animals that are not sensitive to hydrocortisone for additional itch relief.The ZYMOX  Topical Cream is available with and without hydrocortisone.Made in the USA.UsesWounds, cuts, abrasionsDermatitisPromotes healthy skinOn the body, face, paws, body foldsItch relief with 1% hydrocortisoneFeaturesNo stingNon-irritatingNon-toxicCatheter tip for direct applicationWorry-free if lickedNo harsh ingredientsNo parabens, chlorhexidine, benzalkonium chloride, antibiotics, alcoholOnly requires application 1 – 2 times per dayAvailable Size:  1 ozRelief for Itchy Skin Due to Allergies and Other Troublesome Skin ProblemsZYMOX dermatology products for skin provide relief by employing the potent, patented LP3 Enzyme System. They provide natural enzyme-based alternatives to manage complications of allergies and other skin-related issues.
$18.69*

ZYMOX Ear Products Retail Line

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RZES0125WO
ZYMOX Enzymatic Ear Solution Hydrocortisone Free, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

Contains a patented combination of enzymes to aid in removing ear exudate and maintaining ear health.  ZYMOX® Ear Solution makes caring for a pet’s ears easy and fear-free with reduced touching of sensitive ears.  For use on any age dog, cat, exotic, as well as those that are pregnant or lactating.Made in the USA.UsesRemoval of ear exudatePromotes healthy earsSafe for all dogs, cats, small animals, exoticsFor pets who swimPets who live in moist or hot environmentsFeaturesSoothingNon-toxicNo PRE-CLEANING of the earFear-free ear careEasy, once daily applicationNo antibioticsNo corticosteroidsAvailable Size: 1.25 oz No Pre-Cleaning and Once-A-Day Application Create A Fear Free EnvironmentFor over 20 years, the ZYMOX family of ear care products has been offering highly effective products to ensure optimal ear health. At the center of all ZYMOX products is the patented LP3 Enzyme System, the most complete, complex enzyme-based formulation available to pet parents. With the NO PRE-CLEAN protocol, ZYMOX ear care products are good compliments to creating a fear-free experience for the pet.
$21.40*
RZES0125W
ZYMOX Enzymatic Ear Solution with 0.5% Hydrocortisone, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

Contains a patented combination of enzymes to aid in removing ear exudate and maintaining ear health.  ZYMOX® Enzymatic Ear Solution with 0.5% Hydrocortisone promotes healthy ears and relieves itching due to minor inflammation, dermatitis, and other minor skin irritations. ZYMOX Ear Solution’s advanced technology makes caring for a pet’s ears easy and fear-free with reduced touching of sensitive ears.This product contains 0.5% hydrocortisone and is not for use on pregnant or lactating females.Made in the USA.UsesItch ReliefIrritated or inflamed earsRemoval of ear exudatePromotes healthy earsFor dogs and catsFor pets who swimPets who live in moist or hot environmentsFeaturesSoothingNon-toxicNo PRE-CLEANING of the earFear-free ear careEasy, once daily applicationNo antibioticsAvailable Size: 1.25 oz No Pre-Cleaning and Once-A-Day Application Create A Fear Free EnvironmentFor over 20 years, the ZYMOX family of ear care products has been offering highly effective products to ensure optimal ear health. At the center of all ZYMOX products is the patented LP3 Enzyme System, the most complete, complex enzyme-based formulation available to pet parents. With the NO PRE-CLEAN protocol, ZYMOX ear care products are good compliments to creating a fear-free experience for the pet.
$24.70*
RZEC0400
ZYMOX Enzymatic Ear Cleanser, Authentic Product Made in the USA - 4 oz

Average rating of 0 out of 5 stars

Provides an effective, non-toxic and gentle way to manage dirty ears. Features a combination of protein, enzymes and surfactants that make ZYMOX® Ear Cleanser perfect for long term cleaning of non-infected dirty ears.  Does not contain harsh chemicals or detergents that can irritate ears.  Leaves ears smelling fresh.  May be used after completed course of ZYMOX Enzymatic Ear Solution with or without Hydrocortisone. Made in the USA.UsesGentle cleansing of dirty earsFeaturesGentleNon-toxicNon-irritatingLeaves ears smelling clean and freshNo detergents or harsh ingredientsAvailable Sizes: 4 oz and Gallon No Pre-Cleaning and Once-A-Day Application Create A Fear Free EnvironmentFor over 20 years, the ZYMOX family of ear care products has been offering highly effective products to ensure optimal ear health. At the center of all ZYMOX products is the patented LP3 Enzyme System, the most complete, complex enzyme-based formulation available to pet parents. With the NO PRE-CLEAN protocol, ZYMOX ear care products are good compliments to creating a fear-free experience for the pet.
$18.39*
RZFEC0400
ZYMOX Enzymatic Ear Cleanser for Cats & Kittens, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

ZYMOX® Enzymatic Ear Cleanser for Cats and Kittens provides an effective, non-toxic and gentle way to manage dirty ears. Veterinarian recommended and endorsed by TICA, The International Cat Association.  Features a combination of enzymes and surfactants that make ZYMOX Ear Cleanser ideal for cleaning to remove dirt, remove ear wax buildup, promote healthy, ears and prevent ear infections.  Does not contain harsh chemicals or detergents that can irritate ears.  Leaves ears smelling fresh.  May be used after a completed course of ZYMOX Enzymatic Ear Solution for Cats and Kittens. Made in the USA.UsesGentle cleansing of dirty earsFeaturesGentleNon-toxicNon-irritatingLeaves ears smelling clean and freshNo detergents or harsh ingredientsAvailable Size: 4 oz 
$18.39*
RZFES0125
ZYMOX Enzymatic Ear Solution with 0.5% Hydrocortisone for Cats & Kittens, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

ZYMOX® Enzymatic Ear Solution with 0.5% Hydrocortisone for Cats and Kittens for the relief of ear infections and maintaining ear health. Veterinarian recommended and endorsed by TICA, The International Cat Association. ZYMOX Enzymatic Ear Solution with 0.5% Hydrocortisone contains a patented combination of enzymes plus 0.5% hydrocortisone to relieve itching due to minor inflammation, dermatitis, and other minor skin irritations. Easy to use, with no pre-cleaning of the ear prior to application, makes caring for a pet’s ears easy and fear-free with reduced touching of sensitive ears. Contains no antibiotics for harsh ingredients. For use on any age cat or kitten.This product contains 0.5% hydrocortisone and is not for use on pregnant or lactating females.Made in the USA.UsesItch ReliefIrritated or inflamed earsRemoval of ear exudatePromotes healthy earsFeaturesSoothingNon-toxicNo PRE-CLEANING of the earFear-free ear careEasy, once daily applicationNo antibioticsAvailable Size: 1.25 oz
$24.70*

ZYMOX Ear Products Veterinary Line

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1000
ZYMOX Otic Enzymatic Solution With 1% Hydrocortisone, Authentic Product Made in the USA - 1.25 oz

Average rating of 5 out of 5 stars

5
Relief for Acute or Chronic OtitisHighly effective in the management of acute and chronic otitis due to bacterial, fungal or yeast infections without antibiotics.  The powerful enzymatic action of the patented LP3 Enzyme System naturally cleans, disinfects and removes ear exudate while destroying even the most resistant microbes.  ZYMOX Otic’s advanced enzyme technology makes caring for a pet’s ears easy and fear-free with reduced touching of sensitive ears.  For use on any age dog or cat. With 1% hydrocortisone for relief of itching due to minor inflammation, dermatitis or other minor irritations.Made in the USA.UsesAcute and chronic otitisAntibacterial, antifungal, anti-yeastItch reliefIrritated or inflamed earsRemoval of ear exudatePromotes healthy earsFor dogs and catsFor pets who swimPets who live in moist or hot environmentsFeaturesSoothingNon-toxicNo PRE-CLEANING of the earFear-free ear careEasy, once daily applicationNo antibioticsAvailable sizes:  1.25 oz, 4 oz, 8 ozTo order, contact your preferred veterinary distributorManaging Bacterial ResistanceBiofilm producing infections are 10 to 100x more resistant to the effects of antimicrobial agentsWhat is Biofilm?Biofilm is an ill-defined mix of polysaccharides, nucleic acids and proteins encased in a slimy matrix created by microorganisms to house DNA. Biofilm is the believed to be a culprit for antibiotic resistance and the reason many otitis cases are persistent or recurring.  Due to incomplete killing of cells, bacteria can remain hidden in a complex biofilm even after the infection appears to be resolved, patiently waiting for ideal conditions to multiply and re-infect.How Advanced Formula ZYMOX PLUS Otic WorksThe Advanced Formula ZYMOX PLUS features the patented LP3 Enzyme System PLUS four additional enzymes.  The combination of mutanase, dextranase, cellulase, and betagluconase work to attack the complex biolfilm structure, prevent adhesion and metabolize its components.  When combined with the antimicrobial LP3 Enzyme System, the results are antibacterial and antifungal along with effective biofilm removal.Mutanase can exhibit diverse action pattern but fundamentally degrades ẞ-1, 3-glucan to glucose, making it water soluble.Dextranase is an enzyme which catalyzes the endohydrolysis of 1,6-a-glucosidic linkages in dextran resulting in damage to the biofilm.Cellulase is critical to an antibiofilm enzyme preparation, as cellulose is found in most biofilms. Cellulase has been shown to significantly reduce biofilm formation by the pathogen Pseudomonas aeruginosa.Beta glucanase is another important antibiofilm component that provides powerful anticandidal biofilm activity by lysing the glucans that are common in candida biofilms and compose up to 60% of fungal cell walls. Beta-glucan secreted by candida cells within biofilms significantly increase the organism’s resistance to antifungals and enzymatic breakdown of the beta-glucan can make candida more susceptible to destruction.
$26.20*
1000F
ZYMOX Otic Enzymatic Solution, Authentic Product Made in the USA - 1.25 oz

Average rating of 0 out of 5 stars

Highly effective in the management of acute and chronic otitis due to bacterial, fungal or yeast infections without antibiotics.  The powerful enzymatic action of the patented LP3 Enzyme System naturally cleans, disinfects and removes ear exudate while destroying even the most resistant microbes. ZYMOX Otic’s advanced enzyme technology makes caring for a pet’s ears easy and fear-free with reduced touching of sensitive ears.  For use on any age dog, cat, exotics as well as those that are pregnant or lactating. Safe for extended use to manage or prevent.Made in the USA.UsesAcute and chronic otitisAntibacterial, antifungal, anti-yeastIrritated or inflamed earsRemoval of ear exudatePromotes healthy earsFor dogs, cats, small animalsPregnant or lactating female petsFor pets who swimPets who live in moist or hot environmentsFeaturesSoothingNon-toxicNo PRE-CLEANING of the earFear-free ear careEasy, once daily applicationNo antibioticsNo corticosteroidsAvailable sizes:  1.25 oz, 4 oz, 8 ozTo order, contact your preferred veterinary distributorManaging Bacterial ResistanceBiofilm producing infections are 10 to 100x more resistant to the effects of antimicrobial agentsWhat is Biofilm?Biofilm is an ill-defined mix of polysaccharides, nucleic acids and proteins encased in a slimy matrix created by microorganisms to house DNA. Biofilm is the believed to be a culprit for antibiotic resistance and the reason many otitis cases are persistent or recurring.  Due to incomplete killing of cells, bacteria can remain hidden in a complex biofilm even after the infection appears to be resolved, patiently waiting for ideal conditions to multiply and re-infect.How Advanced Formula ZYMOX PLUS Otic WorksThe Advanced Formula ZYMOX PLUS features the patented LP3 Enzyme System PLUS four additional enzymes.  The combination of mutanase, dextranase, cellulase, and betagluconase work to attack the complex biolfilm structure, prevent adhesion and metabolize its components.  When combined with the antimicrobial LP3 Enzyme System, the results are antibacterial and antifungal along with effective biofilm removal.Mutanase can exhibit diverse action pattern but fundamentally degrades ẞ-1, 3-glucan to glucose, making it water soluble.Dextranase is an enzyme which catalyzes the endohydrolysis of 1,6-a-glucosidic linkages in dextran resulting in damage to the biofilm.Cellulase is critical to an antibiofilm enzyme preparation, as cellulose is found in most biofilms. Cellulase has been shown to significantly reduce biofilm formation by the pathogen Pseudomonas aeruginosa.Beta glucanase is another important antibiofilm component that provides powerful anticandidal biofilm activity by lysing the glucans that are common in candida biofilms and compose up to 60% of fungal cell walls. Beta-glucan secreted by candida cells within biofilms significantly increase the organism’s resistance to antifungals and enzymatic breakdown of the beta-glucan can make candida more susceptible to destruction.
$22.39*
1201af
ZYMOX PLUS Advanced Otic Enzymatic Solution Hydrocortisone Free, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

Contains a patented combination of enzymes to provide relief of persistent or recurring ear irritations and promote healthy ears. Advanced Formula ZYMOX Otic features increased potency of the patented LP3 Enzyme System to aid in removing ear exudate PLUS four additional biofilm-reducing enzymes formulated to destroy the hard-to-penetrate biofilm.  This advanced enzyme technology makes caring for your pet’s ears easy with reduced touching of sensitive ears.For use on any age dog, cat, exotic as well as those that are pregnant or lactating.Made in the USA.UsesResistant OtitisAntibacterial, antifungal, anti-yeastAntibiofilm technologyIrritated or inflamed earsRemoval of ear exudatePromotes healthy earsFor dogs and catsFor pets who swimPets who live in moist or hot environmentsFeaturesSoothingNon-toxicNo PRE-CLEANING of the earFear-free ear careEasy, once daily applicationNo antibioticsNo corticosteroidsAvailable sizes:  1.25 ozManaging Bacterial ResistanceBiofilm producing infections are 10 to 100x more resistant to the effects of antimicrobial agentsWhat is Biofilm?Biofilm is an ill-defined mix of polysaccharides, nucleic acids and proteins encased in a slimy matrix created by microorganisms to house DNA. Biofilm is the believed to be a culprit for antibiotic resistance and the reason many otitis cases are persistent or recurring.  Due to incomplete killing of cells, bacteria can remain hidden in a complex biofilm even after the infection appears to be resolved, patiently waiting for ideal conditions to multiply and re-infect.How Advanced Formula ZYMOX PLUS Otic WorksThe Advanced Formula ZYMOX PLUS features the patented LP3 Enzyme System PLUS four additional enzymes.  The combination of mutanase, dextranase, cellulase, and betagluconase work to attack the complex biolfilm structure, prevent adhesion and metabolize its components.  When combined with the antimicrobial LP3 Enzyme System, the results are antibacterial and antifungal along with effective biofilm removal.Mutanase can exhibit diverse action pattern but fundamentally degrades ẞ-1, 3-glucan to glucose, making it water soluble.Dextranase is an enzyme which catalyzes the endohydrolysis of 1,6-a-glucosidic linkages in dextran resulting in damage to the biofilm.Cellulase is critical to an antibiofilm enzyme preparation, as cellulose is found in most biofilms. Cellulase has been shown to significantly reduce biofilm formation by the pathogen Pseudomonas aeruginosa.Beta glucanase is another important antibiofilm component that provides powerful anticandidal biofilm activity by lysing the glucans that are common in candida biofilms and compose up to 60% of fungal cell walls. Beta-glucan secreted by candida cells within biofilms significantly increase the organism’s resistance to antifungals and enzymatic breakdown of the beta-glucan can make candida more susceptible to destruction.
$33.00*
Recommended Product
1201a
ZYMOX PLUS Advanced Otic Enzymatic Solution with 1% Hydrocortisone, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

Contains a patented combination of enzymes to provide relief of persistent or recurring ear irritations and promote healthy ears. Advanced Formula ZYMOX Otic Plus 1% Hydrocortisone features increased potency of the patented LP3 Enzyme System to aid in removing ear exudate PLUS four additional biofilm-reducing enzymes formulated to destroy the hard-to-penetrate biofilm and the addition of 1% Hydrocortisone to reduce itching due to inflammation, dermatitis, and other minor skin irritations.  This advanced enzyme technology makes caring for your pet’s ears easy with reduced touching of sensitive ears.This product contains 1% hydrocortisone and is not for use on pregnant or lactating females.Made in the USA.UsesResistant otitisAntibacterial, antifungal, anti-yeastAntibiofilm technologyItch reliefIrritated or inflamed earsRemoval of ear exudatePromotes healthy earsFor dogs and catsFor pets who swimPets who live in moist or hot environmentsFeaturesSoothingNon-toxicNo PRE-CLEANING of the earFear-free ear careEasy, once daily applicationNo antibioticsAvailable sizes:  1.25 ozManaging Bacterial ResistanceBiofilm producing infections are 10 to 100x more resistant to the effects of antimicrobial agentsWhat is Biofilm?Biofilm is an ill-defined mix of polysaccharides, nucleic acids and proteins encased in a slimy matrix created by microorganisms to house DNA. Biofilm is the believed to be a culprit for antibiotic resistance and the reason many otitis cases are persistent or recurring.  Due to incomplete killing of cells, bacteria can remain hidden in a complex biofilm even after the infection appears to be resolved, patiently waiting for ideal conditions to multiply and re-infect.How Advanced Formula ZYMOX PLUS Otic WorksThe Advanced Formula ZYMOX PLUS features the patented LP3 Enzyme System PLUS four additional enzymes.  The combination of mutanase, dextranase, cellulase, and betagluconase work to attack the complex biolfilm structure, prevent adhesion and metabolize its components.  When combined with the antimicrobial LP3 Enzyme System, the results are antibacterial and antifungal along with effective biofilm removal.Mutanase can exhibit diverse action pattern but fundamentally degrades ẞ-1, 3-glucan to glucose, making it water soluble.Dextranase is an enzyme which catalyzes the endohydrolysis of 1,6-a-glucosidic linkages in dextran resulting in damage to the biofilm.Cellulase is critical to an antibiofilm enzyme preparation, as cellulose is found in most biofilms. Cellulase has been shown to significantly reduce biofilm formation by the pathogen Pseudomonas aeruginosa.Beta glucanase is another important antibiofilm component that provides powerful anticandidal biofilm activity by lysing the glucans that are common in candida biofilms and compose up to 60% of fungal cell walls. Beta-glucan secreted by candida cells within biofilms significantly increase the organism’s resistance to antifungals and enzymatic breakdown of the beta-glucan can make candida more susceptible to destruction.
$36.80*

Oratene Brushless Oral Care

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ROBF0400
Oratene® Enzymatic Brushless Breath Freshener, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

Keep pet’s teeth and gums clean and fresh. Oratene® Breath Freshener delivers a gentle mist to freshen any pet’s breath. Features two complete enzyme systems based on 40 years of advanced enzyme technology.  Contains the patented LP3 Enzyme System, the most complete, natural multi-complex enzyme system available to eliminate odor-causing bacteria PLUS the MD2 mutanase and dextranase enzyme system to inhibit plaque formation. Recommended for all pets in need of gentle, non-drying everyday oral care. Especially beneficial to pets prescribed medications which may cause Xerostomia. Does not contain xylitol, alcohol, chlorhexidine, dyes, or detergent.Over 900 pumps per bottleMade in the USA.UsesClean teethFresh breathInhibits plaque formationPromotes periodontal healthBalances oral floraXerostomia (Dry Mouth)FeaturesGentle misterReadily acceptedFlavorlessNon-irritatingNon-dryingNo xylitol - safe for dogs and catsWon’t cause excess salivationNo chlorhexidine, alcohol, detergents, dyesAvailable Size:  4 oz Easy and Effective Brushless Oral CareOratene Brushless Oral Care offers superior oral protection against bad breath, plaque and periodontal disease. Oratene delivers two complete, patented enzyme systems not found in any other enzymatic oral care line. The oral care products effectively inhibit the bacteria that cause bad breath, boost the natural oral flora, help protect against gum disease and dissolve plaque biofilm.
$13.20*
ROWA0400
Oratene® Enzymatic Brushless Water Additive, Authentic Product Made in the USA - 4 oz

Average rating of 0 out of 5 stars

The simple way to care for a pet’s oral care and keep teeth and gums clean, fresh and healthy. This flavorless concentrate is added to fresh drinking water daily and provides a convenient way to support normal periodontal health.  Oratene® Water Additive features two complete enzyme systems based on 40 years of advanced enzyme technology.  Contains the patented LP3 Enzyme System, the most complete, natural multi-complex enzyme system available to eliminate odor-causing bacteria PLUS the MD2 mutanase and dextranase enzyme system to inhibit plaque formation. Recommended for all pets in need of gentle, non-drying everyday oral care.  Especially beneficial to those prescribed medications which may cause Xerostomia. Does not contain xylitol, alcohol, chlorhexidine, detergents or dyes.1 - 4 oz bottle makes 15 gallonsMade in the USA.UsesClean teethFresh breathPlaque inhibitionPromotes periodontal healthBalances oral floraXerostomia (Dry Mouth)FeaturesNo brushing neededReadily acceptedEffective oral care with every lap of waterFlavorlessNon-irritatingNon-dryingNo xylitol - safe for dogs and catsWon’t cause excess salivationNo chlorhexidine, alcohol, detergents, dyesAvailable Sizes:  4 oz and 8 oz Easy and Effective Brushless Oral CareOratene Brushless Oral Care offers superior oral protection against bad breath, plaque and periodontal disease. Oratene delivers two complete, patented enzyme systems not found in any other enzymatic oral care line. The oral care products effectively inhibit the bacteria that cause bad breath, boost the natural oral flora, help protect against gum disease and dissolve plaque biofilm.
$20.30*
ROCAG0100
Oratene® Enzymatic Brushless Oral Gel, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

This clear gel form provides maximum enzyme contact for relief for serious conditions such as periodontal disease, gingivitis, stomatitis and inflamed gums and ulcerations.  Oratene® Oral Gel is the most potent enzyme formulation in the Oratene product line.  Oratene is based on 40 years of advanced enzyme technology and is the most complete, natural multi-complex available to support normal gum health.  A preferred chlorhexidine replacement.  Features a mildly sweet, non-bitter flavor. Won’t stain the teeth or cause excess salivation.  Previously known as Oratene Antiseptic Gel.Made in the USA.UsesInflamed gumsPeriodontal diseaseGingivitisStomatitisMouth ulcerationsPromotes normal periodontal healthPost dental prophyPost extractionFeaturesMaximum enzyme contactReadily acceptedFlavorlessNon-irritatingNon-dryingNo xylitol - safe for dogs and catsWon’t cause excess salivationNo chlorhexidine, alcohol, detergents, dyesAvailable Size: 1 oz Easy and Effective Brushless Oral CareOratene Brushless Oral Care offers superior oral protection against bad breath, plaque and periodontal disease. Oratene delivers two complete, patented enzyme systems not found in any other enzymatic oral care line. The oral care products effectively inhibit the bacteria that cause bad breath, boost the natural oral flora, help protect against gum disease and dissolve plaque biofilm.
$13.00*
RODG0250
Oratene® Enzymatic Brushless Toothpaste Gel, Authentic Product Made in the USA

Average rating of 5 out of 5 stars

5
This clear gel form provides maximum enzyme contact to keep pet’s teeth and gums clean, fresh and support normal periodontal health. Oratene® Toothpaste Gel includes two complete enzyme systems based on 40 years of advanced enzyme technology. Contains the patented LP3 Enzyme System, the most complete, natural multi-complex enzyme system available to eliminate odor-causing bacteria PLUS the MD2 mutanase and dextranase enzyme system to inhibit plaque formation. Recommended for all pets in need of gentle, non-drying everyday oral care. Especially beneficial to pets prescribed medications which may cause Xerostomia. May be applied with a toothbrush or finger.  No brushing required.  Pleasant tasting.  Does not contain Xylitol, alcohol, chlorhexidine, dyes, or detergent.1- 2.5 oz tube provides up to 4 months supplyMade in the USA.UsesClean teethFresh breathPlaque inhibitionPromotes periodontal healthBalances oral floraXerostomia (Dry Mouth)FeaturesNo brushing neededNo rinsing neededCan be used with a brush or applied by handReadily acceptedFlavorlessNon-irritatingNon-dryingNo xylitol - safe for dogs and catsWon’t cause excess salivationNo chlorhexidine, alcohol, detergents, dyesAvailable Size: 2.5 oz Easy and Effective Brushless Oral CareOratene Brushless Oral Care offers superior oral protection against bad breath, plaque and periodontal disease. Oratene delivers two complete, patented enzyme systems not found in any other enzymatic oral care line. The oral care products effectively inhibit the bacteria that cause bad breath, boost the natural oral flora, help protect against gum disease and dissolve plaque biofilm.
$16.50*

ZYMOX Equine Defense

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REDAFS1200
Equine Defense Advanced Formula Shampoo, Authentic Product Made in the USA - 12 oz

Average rating of 0 out of 5 stars

ZYMOX® Equine Defense Advanced Formula Shampoo is used to cleanse and soothe dry, irritated skin. Formulated with the antimicrobial LP3 Enzyme System plus Vitamin D3 and oat extract to hydrate, nourish, and promote healthy skin.  Hypoallergenic, pH balanced, and safe for horses and livestock of all ages. Free of harsh detergents, parabens, and silicone to help keep the animal skin and coat healthy and shiny.Does not contain silicone or parabens.Made in the USA.UsesGentle cleansingHydrates dry, itchy skinNourishes coatPromotes healthy skinSheath cleansingFeaturesSoothingConditioningDetangling for the mane and tailMoisturizingPleasant smellingDries non-greasyLeave on or rinse offUse as a lotionNon-toxic, worry-free if lickedNo silicones or parabensNo steroidsTest cleanAvailable Sizes: 12 oz and GallonManage Conditions of the Hoof and HideThe ZYMOX Equine Defense products line utilizes the advanced technology of the patented LP3 Enzyme System for the management of chronic skin and hoof conditions. Containing no steroids, antibiotics, or petroleum by-products. These products are gentle and soothing to irritated skin, won’t harm surrounding healthy tissue, and don’t have the adverse effects associated with other conventional treatments.
$14.80*
REDAFC1200
Equine Defense Advanced Formula Leave-On Conditioner, Authentic Product Made in the USA - 12 oz

Average rating of 0 out of 5 stars

ZYMOX® Equine Defense Advanced Formula Leave-On Conditioner is used to condition, soothe and moisturize dry, irritated skin, and detangle mane and tail. Formulated with the antimicrobial LP3 Enzyme System plus Vitamin D3 and oat extract to hydrate and provide a powerful protective skin layer. Hypoallergenic, pH balanced, and safe for horses and livestock of all ages. Free of parabens, and silicone to help keep the animal skin and coat healthy and shiny.Does not contain silicone or parabens.Made in the USA.UsesConditioning of skinIrritated skinPromotes skin healthFeaturesSoothingConditioningDetangling for the mane and tailMoisturizingPleasant smellingDries non-greasyLeave on or rinse offUse as a lotionNon-toxic, worry-free if lickedNo silicones or parabensNo steroidsTest cleanAvailable Sizes: 12 oz and GallonManage Conditions of the Hoof and HideThe ZYMOX Equine Defense products line utilizes the advanced technology of the patented LP3 Enzyme System for the management of chronic skin and hoof conditions. Containing no steroids, antibiotics, or petroleum by-products. These products are gentle and soothing to irritated skin, won’t harm surrounding healthy tissue, and don’t have the adverse effects associated with other conventional treatments.
$14.80*
REDWSC0250
Equine Defense Topical Cream, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

ZYMOX® Equine Defense Cream features the patented LP3 Enzyme System which blends a concentrated combination of protein and enzymes plus skin-soothing aloe vera in a gentle, non-toxic water-based formulation to help promote healthy skin. Ideal for application for small targeted areas on head, muzzle,body, legs and hooves.Does not contain harsh ingredients, chemicals, antibiotics, or steroids. Made in the USA.UsesPromotes healthy skinSkin irritations or abrasionsWounds or cutsScratchesFeaturesNo stingSoothing reliefNon-irritatingNon-toxicWorry-free if lickedNo harsh ingredientsNo antibiotics or steroidsNo oilsNo astringents or alcoholTest cleanAvailable Size: 2.5 ozManage Conditions of the Hoof and HideZYMOX Equine Defense products utilize the advanced technology of the patented LP3 Enzyme System for the management of chronic skin and hoof conditions. Containing no steroids, antibiotics or petroleum by-products. These products are gentle and soothing to irritated skin, won’t harm surrounding healthy tissue, and don’t have the adverse effects associated with other conventional treatments.
$19.30*
REDWSS080
Equine Defense Enzyme Formula Topical Spray, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

ZYMOX® Equine Defense Spray features the patented LP3 Enzyme System. Which blends a concentrated combination of protein and enzymes plus skin-soothing aloe vera in a gentle, non-toxic, water-based formulation that promotes healthy skin.  Ideal for application to the body, legs, and hooves.Does not contain harsh astringents, alcohols, chemicals, antibiotics, or steroids. Made in the USA.UsesPromotes healthy skinSkin irritations or abrasionsWounds or cutsScratchesFeaturesNo stingSoothing reliefNon-irritatingNon-toxicWorry-free if lickedNo harsh ingredientsNo antibiotics or steroidsNo oilsNo astringents or alcoholTest cleanAvailable Size: 8 ozManage Conditions of the Hoof and HideThe ZYMOX Equine Defense products line utilizes the advanced technology of the patented LP3 Enzyme System for the management of chronic skin and hoof conditions. Containing no steroids, antibiotics, or petroleum by-products. These products are gentle and soothing to irritated skin, won’t harm surrounding healthy tissue, and don’t have the adverse effects associated with other conventional treatments.
$22.30*