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Healthy Ears, Happy Pet

Keep your pet’s ears healthy and fresh with ZYMOX® Ear Care products for dogs, cats, and small animals. These gentle, non-toxic, no-sting products harness the power of enzymes with a natural, multi-complex enzyme formulation that works with less touch to sensitive ears—helping you create a positive ear care experience.
Trusted by veterinarians, ZYMOX has been helping pets find soothing relief for over 20 years. Whether you have an active dog who loves to swim, a cat prone to irritated ears, a pet affected by allergies or smelly ears, ZYMOX has a product to help keep your pet happy and their ears healthy.

For dirty ears, ZYMOX Ear Cleanser combines protein, enzymes, and surfactants to gently cleanse. For those ears with a build-up of exudate, ZYMOX Ear Solution provides two options with the patented combination of enzymes: ZYMOX Ear Solution with added 0.5% Hydrocortisone for itch relief and ZYMOX Ear Solution that can be used for a longer duration and is great for pets sensitive to corticosteroids.

ZYMOX Ear Products Line

RZEW
ZYMOX Advanced Enzymatic Ear Wipes

Average rating of 0 out of 5 stars

ZYMOX® Ear Wipes are clinically proven and dermatologist tested hypoallergenic and non-irritating, and are perfect for daily use on dog or cats’ ears. * Each 6 oz. jar contains 100 wipes that feature a textured back for easy grip by the pet parent or groomer. Contain Aloe Vera which helps to alleviate temporary redness and discomfort by calming and moisturizing the skin, and menthyl lactate that helps to soothe irritated skin. Fragrance free, dye free and free of alcohol, harsh chemicals and detergents that can irritate pets’ ears. Use wipes only with other ZYMOX products to retain the enzymes’ efficiency and optimized results. Jar allows easy storage and is convenient for traveling.  *Clinically proven there was no indication of a potential to elicit skin irritation or sensitization (contact allergy).Made in the USA.
$18.70*
RZEC0400
ZYMOX Enzymatic Ear Cleanser, Authentic Product Made in the USA - 4 oz

Average rating of 0 out of 5 stars

Provides an effective, non-toxic and gentle way to manage dirty ears. Features a combination of protein, enzymes and surfactants that make ZYMOX® Ear Cleanser perfect for long term cleaning of non-infected dirty ears.  Does not contain harsh chemicals or detergents that can irritate ears.  Leaves ears smelling fresh.  May be used after completed course of ZYMOX Enzymatic Ear Solution with or without Hydrocortisone. Made in the USA.UsesGentle cleansing of dirty earsFeaturesGentleNon-toxicNon-irritatingLeaves ears smelling clean and freshNo detergents or harsh ingredientsAvailable Sizes: 4 oz and Gallon No Pre-Cleaning and Once-A-Day Application Create A Fear Free EnvironmentFor over 20 years, the ZYMOX family of ear care products has been offering highly effective products to ensure optimal ear health. At the center of all ZYMOX products is the patented LP3 Enzyme System, the most complete, complex enzyme-based formulation available to pet parents. With the NO PRE-CLEAN protocol, ZYMOX ear care products are good compliments to creating a fear-free experience for the pet.
$18.39*
RZES0125WO
ZYMOX Enzymatic Ear Solution Hydrocortisone Free, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

Contains a patented combination of enzymes to aid in removing ear exudate and maintaining ear health.  ZYMOX® Ear Solution makes caring for a pet’s ears easy and fear-free with reduced touching of sensitive ears.  For use on any age dog, cat, exotic, as well as those that are pregnant or lactating.Made in the USA.UsesRemoval of ear exudatePromotes healthy earsSafe for all dogs, cats, small animals, exoticsFor pets who swimPets who live in moist or hot environmentsFeaturesSoothingNon-toxicNo PRE-CLEANING of the earFear-free ear careEasy, once daily applicationNo antibioticsNo corticosteroidsAvailable Size: 1.25 oz No Pre-Cleaning and Once-A-Day Application Create A Fear Free EnvironmentFor over 20 years, the ZYMOX family of ear care products has been offering highly effective products to ensure optimal ear health. At the center of all ZYMOX products is the patented LP3 Enzyme System, the most complete, complex enzyme-based formulation available to pet parents. With the NO PRE-CLEAN protocol, ZYMOX ear care products are good compliments to creating a fear-free experience for the pet.
$21.40*
RZES0125W
ZYMOX Enzymatic Ear Solution with 0.5% Hydrocortisone, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

Contains a patented combination of enzymes to aid in removing ear exudate and maintaining ear health.  ZYMOX® Enzymatic Ear Solution with 0.5% Hydrocortisone promotes healthy ears and relieves itching due to minor inflammation, dermatitis, and other minor skin irritations. ZYMOX Ear Solution’s advanced technology makes caring for a pet’s ears easy and fear-free with reduced touching of sensitive ears.This product contains 0.5% hydrocortisone and is not for use on pregnant or lactating females.Made in the USA.UsesItch ReliefIrritated or inflamed earsRemoval of ear exudatePromotes healthy earsFor dogs and catsFor pets who swimPets who live in moist or hot environmentsFeaturesSoothingNon-toxicNo PRE-CLEANING of the earFear-free ear careEasy, once daily applicationNo antibioticsAvailable Size: 1.25 oz No Pre-Cleaning and Once-A-Day Application Create A Fear Free EnvironmentFor over 20 years, the ZYMOX family of ear care products has been offering highly effective products to ensure optimal ear health. At the center of all ZYMOX products is the patented LP3 Enzyme System, the most complete, complex enzyme-based formulation available to pet parents. With the NO PRE-CLEAN protocol, ZYMOX ear care products are good compliments to creating a fear-free experience for the pet.
$24.70*
1000
ZYMOX Otic Enzymatic Solution With 1% Hydrocortisone, Authentic Product Made in the USA - 1.25 oz

Average rating of 5 out of 5 stars

5
Relief for Acute or Chronic OtitisHighly effective in the management of acute and chronic otitis due to bacterial, fungal or yeast infections without antibiotics.  The powerful enzymatic action of the patented LP3 Enzyme System naturally cleans, disinfects and removes ear exudate while destroying even the most resistant microbes.  ZYMOX Otic’s advanced enzyme technology makes caring for a pet’s ears easy and fear-free with reduced touching of sensitive ears.  For use on any age dog or cat. With 1% hydrocortisone for relief of itching due to minor inflammation, dermatitis or other minor irritations.Made in the USA.UsesAcute and chronic otitisAntibacterial, antifungal, anti-yeastItch reliefIrritated or inflamed earsRemoval of ear exudatePromotes healthy earsFor dogs and catsFor pets who swimPets who live in moist or hot environmentsFeaturesSoothingNon-toxicNo PRE-CLEANING of the earFear-free ear careEasy, once daily applicationNo antibioticsAvailable sizes:  1.25 oz, 4 oz, 8 ozTo order, contact your preferred veterinary distributorManaging Bacterial ResistanceBiofilm producing infections are 10 to 100x more resistant to the effects of antimicrobial agentsWhat is Biofilm?Biofilm is an ill-defined mix of polysaccharides, nucleic acids and proteins encased in a slimy matrix created by microorganisms to house DNA. Biofilm is the believed to be a culprit for antibiotic resistance and the reason many otitis cases are persistent or recurring.  Due to incomplete killing of cells, bacteria can remain hidden in a complex biofilm even after the infection appears to be resolved, patiently waiting for ideal conditions to multiply and re-infect.How Advanced Formula ZYMOX PLUS Otic WorksThe Advanced Formula ZYMOX PLUS features the patented LP3 Enzyme System PLUS four additional enzymes.  The combination of mutanase, dextranase, cellulase, and betagluconase work to attack the complex biolfilm structure, prevent adhesion and metabolize its components.  When combined with the antimicrobial LP3 Enzyme System, the results are antibacterial and antifungal along with effective biofilm removal.Mutanase can exhibit diverse action pattern but fundamentally degrades ẞ-1, 3-glucan to glucose, making it water soluble.Dextranase is an enzyme which catalyzes the endohydrolysis of 1,6-a-glucosidic linkages in dextran resulting in damage to the biofilm.Cellulase is critical to an antibiofilm enzyme preparation, as cellulose is found in most biofilms. Cellulase has been shown to significantly reduce biofilm formation by the pathogen Pseudomonas aeruginosa.Beta glucanase is another important antibiofilm component that provides powerful anticandidal biofilm activity by lysing the glucans that are common in candida biofilms and compose up to 60% of fungal cell walls. Beta-glucan secreted by candida cells within biofilms significantly increase the organism’s resistance to antifungals and enzymatic breakdown of the beta-glucan can make candida more susceptible to destruction.
$26.20*
1000F
ZYMOX Otic Enzymatic Solution, Authentic Product Made in the USA - 1.25 oz

Average rating of 0 out of 5 stars

Highly effective in the management of acute and chronic otitis due to bacterial, fungal or yeast infections without antibiotics.  The powerful enzymatic action of the patented LP3 Enzyme System naturally cleans, disinfects and removes ear exudate while destroying even the most resistant microbes. ZYMOX Otic’s advanced enzyme technology makes caring for a pet’s ears easy and fear-free with reduced touching of sensitive ears.  For use on any age dog, cat, exotics as well as those that are pregnant or lactating. Safe for extended use to manage or prevent.Made in the USA.UsesAcute and chronic otitisAntibacterial, antifungal, anti-yeastIrritated or inflamed earsRemoval of ear exudatePromotes healthy earsFor dogs, cats, small animalsPregnant or lactating female petsFor pets who swimPets who live in moist or hot environmentsFeaturesSoothingNon-toxicNo PRE-CLEANING of the earFear-free ear careEasy, once daily applicationNo antibioticsNo corticosteroidsAvailable sizes:  1.25 oz, 4 oz, 8 ozTo order, contact your preferred veterinary distributorManaging Bacterial ResistanceBiofilm producing infections are 10 to 100x more resistant to the effects of antimicrobial agentsWhat is Biofilm?Biofilm is an ill-defined mix of polysaccharides, nucleic acids and proteins encased in a slimy matrix created by microorganisms to house DNA. Biofilm is the believed to be a culprit for antibiotic resistance and the reason many otitis cases are persistent or recurring.  Due to incomplete killing of cells, bacteria can remain hidden in a complex biofilm even after the infection appears to be resolved, patiently waiting for ideal conditions to multiply and re-infect.How Advanced Formula ZYMOX PLUS Otic WorksThe Advanced Formula ZYMOX PLUS features the patented LP3 Enzyme System PLUS four additional enzymes.  The combination of mutanase, dextranase, cellulase, and betagluconase work to attack the complex biolfilm structure, prevent adhesion and metabolize its components.  When combined with the antimicrobial LP3 Enzyme System, the results are antibacterial and antifungal along with effective biofilm removal.Mutanase can exhibit diverse action pattern but fundamentally degrades ẞ-1, 3-glucan to glucose, making it water soluble.Dextranase is an enzyme which catalyzes the endohydrolysis of 1,6-a-glucosidic linkages in dextran resulting in damage to the biofilm.Cellulase is critical to an antibiofilm enzyme preparation, as cellulose is found in most biofilms. Cellulase has been shown to significantly reduce biofilm formation by the pathogen Pseudomonas aeruginosa.Beta glucanase is another important antibiofilm component that provides powerful anticandidal biofilm activity by lysing the glucans that are common in candida biofilms and compose up to 60% of fungal cell walls. Beta-glucan secreted by candida cells within biofilms significantly increase the organism’s resistance to antifungals and enzymatic breakdown of the beta-glucan can make candida more susceptible to destruction.
$22.39*
1201af
ZYMOX PLUS Advanced Otic Enzymatic Solution Hydrocortisone Free, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

Contains a patented combination of enzymes to provide relief of persistent or recurring ear irritations and promote healthy ears. Advanced Formula ZYMOX Otic features increased potency of the patented LP3 Enzyme System to aid in removing ear exudate PLUS four additional biofilm-reducing enzymes formulated to destroy the hard-to-penetrate biofilm.  This advanced enzyme technology makes caring for your pet’s ears easy with reduced touching of sensitive ears.For use on any age dog, cat, exotic as well as those that are pregnant or lactating.Made in the USA.UsesResistant OtitisAntibacterial, antifungal, anti-yeastAntibiofilm technologyIrritated or inflamed earsRemoval of ear exudatePromotes healthy earsFor dogs and catsFor pets who swimPets who live in moist or hot environmentsFeaturesSoothingNon-toxicNo PRE-CLEANING of the earFear-free ear careEasy, once daily applicationNo antibioticsNo corticosteroidsAvailable sizes:  1.25 ozManaging Bacterial ResistanceBiofilm producing infections are 10 to 100x more resistant to the effects of antimicrobial agentsWhat is Biofilm?Biofilm is an ill-defined mix of polysaccharides, nucleic acids and proteins encased in a slimy matrix created by microorganisms to house DNA. Biofilm is the believed to be a culprit for antibiotic resistance and the reason many otitis cases are persistent or recurring.  Due to incomplete killing of cells, bacteria can remain hidden in a complex biofilm even after the infection appears to be resolved, patiently waiting for ideal conditions to multiply and re-infect.How Advanced Formula ZYMOX PLUS Otic WorksThe Advanced Formula ZYMOX PLUS features the patented LP3 Enzyme System PLUS four additional enzymes.  The combination of mutanase, dextranase, cellulase, and betagluconase work to attack the complex biolfilm structure, prevent adhesion and metabolize its components.  When combined with the antimicrobial LP3 Enzyme System, the results are antibacterial and antifungal along with effective biofilm removal.Mutanase can exhibit diverse action pattern but fundamentally degrades ẞ-1, 3-glucan to glucose, making it water soluble.Dextranase is an enzyme which catalyzes the endohydrolysis of 1,6-a-glucosidic linkages in dextran resulting in damage to the biofilm.Cellulase is critical to an antibiofilm enzyme preparation, as cellulose is found in most biofilms. Cellulase has been shown to significantly reduce biofilm formation by the pathogen Pseudomonas aeruginosa.Beta glucanase is another important antibiofilm component that provides powerful anticandidal biofilm activity by lysing the glucans that are common in candida biofilms and compose up to 60% of fungal cell walls. Beta-glucan secreted by candida cells within biofilms significantly increase the organism’s resistance to antifungals and enzymatic breakdown of the beta-glucan can make candida more susceptible to destruction.
$33.00*
Recommended Product
1201a
ZYMOX PLUS Advanced Otic Enzymatic Solution with 1% Hydrocortisone, Authentic Product Made in the USA

Average rating of 0 out of 5 stars

Contains a patented combination of enzymes to provide relief of persistent or recurring ear irritations and promote healthy ears. Advanced Formula ZYMOX Otic Plus 1% Hydrocortisone features increased potency of the patented LP3 Enzyme System to aid in removing ear exudate PLUS four additional biofilm-reducing enzymes formulated to destroy the hard-to-penetrate biofilm and the addition of 1% Hydrocortisone to reduce itching due to inflammation, dermatitis, and other minor skin irritations.  This advanced enzyme technology makes caring for your pet’s ears easy with reduced touching of sensitive ears.This product contains 1% hydrocortisone and is not for use on pregnant or lactating females.Made in the USA.UsesResistant otitisAntibacterial, antifungal, anti-yeastAntibiofilm technologyItch reliefIrritated or inflamed earsRemoval of ear exudatePromotes healthy earsFor dogs and catsFor pets who swimPets who live in moist or hot environmentsFeaturesSoothingNon-toxicNo PRE-CLEANING of the earFear-free ear careEasy, once daily applicationNo antibioticsAvailable sizes:  1.25 ozManaging Bacterial ResistanceBiofilm producing infections are 10 to 100x more resistant to the effects of antimicrobial agentsWhat is Biofilm?Biofilm is an ill-defined mix of polysaccharides, nucleic acids and proteins encased in a slimy matrix created by microorganisms to house DNA. Biofilm is the believed to be a culprit for antibiotic resistance and the reason many otitis cases are persistent or recurring.  Due to incomplete killing of cells, bacteria can remain hidden in a complex biofilm even after the infection appears to be resolved, patiently waiting for ideal conditions to multiply and re-infect.How Advanced Formula ZYMOX PLUS Otic WorksThe Advanced Formula ZYMOX PLUS features the patented LP3 Enzyme System PLUS four additional enzymes.  The combination of mutanase, dextranase, cellulase, and betagluconase work to attack the complex biolfilm structure, prevent adhesion and metabolize its components.  When combined with the antimicrobial LP3 Enzyme System, the results are antibacterial and antifungal along with effective biofilm removal.Mutanase can exhibit diverse action pattern but fundamentally degrades ẞ-1, 3-glucan to glucose, making it water soluble.Dextranase is an enzyme which catalyzes the endohydrolysis of 1,6-a-glucosidic linkages in dextran resulting in damage to the biofilm.Cellulase is critical to an antibiofilm enzyme preparation, as cellulose is found in most biofilms. Cellulase has been shown to significantly reduce biofilm formation by the pathogen Pseudomonas aeruginosa.Beta glucanase is another important antibiofilm component that provides powerful anticandidal biofilm activity by lysing the glucans that are common in candida biofilms and compose up to 60% of fungal cell walls. Beta-glucan secreted by candida cells within biofilms significantly increase the organism’s resistance to antifungals and enzymatic breakdown of the beta-glucan can make candida more susceptible to destruction.
$36.80*

Which ZYMOX Ear Product Should be Used?

Product Otic Blue Otic Green Otic Plus Red Otic Plus Yellow Ear Solution. Ear Solution Ear Cleanser Ear Wipes
Hydrocortisone 1.0% 0% 1.0% 0% 0.5% 0% 0% 0%
Exudate yes yes yes yes
Lives in Humid Climate or Swims yes yes yes yes yes yes yes yes
Exotics or Pregnant/Lactating yes yes yes yes yes
Allergies yes yes yes yes yes yes
Itchy, Smelly Ears yes yes yes
Occasional Ocurrences yes yes
Maintenance/Prevention yes yes yes yes
Dirty Ears yes yes
Inflammation yes yes yes
Persistent, Recurring yes yes

Learn More About ZYMOX® Ear Care Products

ZYMOX® Otic Solutions, Red vs Gold – Which to Use
ZYMOX® Otic Solutions – Blue vs Green – Which to Use
ZYMOX® Ear Cleanser
ZYMOX® Ear Solutions for Dogs and Cats with Problem Ears

FAQ

ZYMOX® Ear Solution will clean out exudate, help relieve irritations, and keep the ear clean. ZYMOX® Ear Solution is effective in maintenance of the ears, or to help with itching and discharge especially during the allergy season

You should not use any other ear preparations before or during applications of ZYMOX® Ear Solution because the enzyme activity that is present could become interrupted. The enzyme work best in a dirty environment. The use of ZYMOX® Ear Cleanser is only recommended after using a full course of ZYMOX® Ear Solution to keep dirty ears clean.

The ZYMOX® Ear Cleanser is ideal for cleaning waxy, dirty ears. It is not always necessary to clean ears.

ZYMOX® Ear Solution is to clean out troublesome exudate. If ear wax or dirt seems to be causing the odor, then ZYMOX® Ear Cleanser may be used.

No problem. Just wait 24 hours and start then.

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Proudly Made in the USA

PKB Animal Health Inc. is committed to providing quality products proudly made in the USA that are safe, effective and free of harmful ingredients so animals can lead healthy, happy lives.