ZYMOX PLUS Advanced Otic Enzymatic Solution with 1% Hydrocortisone, Authentic Product Made in the USA

Contains a patented combination of enzymes to provide relief of persistent or recurring ear irritations and promote healthy ears. Advanced Formula ZYMOX Otic features increased potency of the patented LP3 Enzyme System to aid in removing ear exudate PLUS four additional biofilm-reducing enzymes formulated to destroy the hard-to-penetrate biofilm.  This advanced enzyme technology makes caring for your pet’s ears easy with reduced touching of sensitive ears.For use on any age dog, cat, exotic as well as those that are pregnant or lactating.Made in the USA.UsesResistant OtitisAntibacterial, antifungal, anti-yeastAntibiofilm technologyIrritated or inflamed earsRemoval of ear exudatePromotes healthy earsFor dogs and catsFor pets who swimPets who live in moist or hot environmentsFeaturesSoothingNon-toxicNo PRE-CLEANING of the earFear-free ear careEasy, once daily applicationNo antibioticsNo corticosteroidsAvailable sizes:  1.25 ozManaging Bacterial ResistanceBiofilm producing infections are 10 to 100x more resistant to the effects of antimicrobial agentsWhat is Biofilm?Biofilm is an ill-defined mix of polysaccharides, nucleic acids and proteins encased in a slimy matrix created by microorganisms to house DNA. Biofilm is the believed to be a culprit for antibiotic resistance and the reason many otitis cases are persistent or recurring.  Due to incomplete killing of cells, bacteria can remain hidden in a complex biofilm even after the infection appears to be resolved, patiently waiting for ideal conditions to multiply and re-infect.How Advanced Formula ZYMOX PLUS Otic WorksThe Advanced Formula ZYMOX PLUS features the patented LP3 Enzyme System PLUS four additional enzymes.  The combination of mutanase, dextranase, cellulase, and betagluconase work to attack the complex biolfilm structure, prevent adhesion and metabolize its components.  When combined with the antimicrobial LP3 Enzyme System, the results are antibacterial and antifungal along with effective biofilm removal.Mutanase can exhibit diverse action pattern but fundamentally degrades ẞ-1, 3-glucan to glucose, making it water soluble.Dextranase is an enzyme which catalyzes the endohydrolysis of 1,6-a-glucosidic linkages in dextran resulting in damage to the biofilm.Cellulase is critical to an antibiofilm enzyme preparation, as cellulose is found in most biofilms. Cellulase has been shown to significantly reduce biofilm formation by the pathogen Pseudomonas aeruginosa.Beta glucanase is another important antibiofilm component that provides powerful anticandidal biofilm activity by lysing the glucans that are common in candida biofilms and compose up to 60% of fungal cell walls. Beta-glucan secreted by candida cells within biofilms significantly increase the organism’s resistance to antifungals and enzymatic breakdown of the beta-glucan can make candida more susceptible to destruction.

Relief for Acute or Chronic OtitisHighly effective in the management of acute and chronic otitis due to bacterial, fungal or yeast infections without antibiotics.  The powerful enzymatic action of the patented LP3 Enzyme System naturally cleans, disinfects and removes ear exudate while destroying even the most resistant microbes.  ZYMOX Otic’s advanced enzyme technology makes caring for a pet’s ears easy and fear-free with reduced touching of sensitive ears.  For use on any age dog or cat. With 1% hydrocortisone for relief of itching due to minor inflammation, dermatitis or other minor irritations.Made in the USA.UsesAcute and chronic otitisAntibacterial, antifungal, anti-yeastItch reliefIrritated or inflamed earsRemoval of ear exudatePromotes healthy earsFor dogs and catsFor pets who swimPets who live in moist or hot environmentsFeaturesSoothingNon-toxicNo PRE-CLEANING of the earFear-free ear careEasy, once daily applicationNo antibioticsAvailable sizes:  1.25 oz, 4 oz, 8 ozTo order, contact your preferred veterinary distributorManaging Bacterial ResistanceBiofilm producing infections are 10 to 100x more resistant to the effects of antimicrobial agentsWhat is Biofilm?Biofilm is an ill-defined mix of polysaccharides, nucleic acids and proteins encased in a slimy matrix created by microorganisms to house DNA. Biofilm is the believed to be a culprit for antibiotic resistance and the reason many otitis cases are persistent or recurring.  Due to incomplete killing of cells, bacteria can remain hidden in a complex biofilm even after the infection appears to be resolved, patiently waiting for ideal conditions to multiply and re-infect.How Advanced Formula ZYMOX PLUS Otic WorksThe Advanced Formula ZYMOX PLUS features the patented LP3 Enzyme System PLUS four additional enzymes.  The combination of mutanase, dextranase, cellulase, and betagluconase work to attack the complex biolfilm structure, prevent adhesion and metabolize its components.  When combined with the antimicrobial LP3 Enzyme System, the results are antibacterial and antifungal along with effective biofilm removal.Mutanase can exhibit diverse action pattern but fundamentally degrades ẞ-1, 3-glucan to glucose, making it water soluble.Dextranase is an enzyme which catalyzes the endohydrolysis of 1,6-a-glucosidic linkages in dextran resulting in damage to the biofilm.Cellulase is critical to an antibiofilm enzyme preparation, as cellulose is found in most biofilms. Cellulase has been shown to significantly reduce biofilm formation by the pathogen Pseudomonas aeruginosa.Beta glucanase is another important antibiofilm component that provides powerful anticandidal biofilm activity by lysing the glucans that are common in candida biofilms and compose up to 60% of fungal cell walls. Beta-glucan secreted by candida cells within biofilms significantly increase the organism’s resistance to antifungals and enzymatic breakdown of the beta-glucan can make candida more susceptible to destruction.

ZYMOX® Ear Wipes are clinically proven and dermatologist tested hypoallergenic and non-irritating, and are perfect for daily use on dog or cats’ ears. * Each 6 oz. jar contains 100 wipes that feature a textured back for easy grip by the pet parent or groomer. Contain Aloe Vera which helps to alleviate temporary redness and discomfort by calming and moisturizing the skin, and menthyl lactate that helps to soothe irritated skin. Fragrance free, dye free and free of alcohol, harsh chemicals and detergents that can irritate pets’ ears. Use wipes only with other ZYMOX products to retain the enzymes’ efficiency and optimized results. Jar allows easy storage and is convenient for traveling.  *Clinically proven there was no indication of a potential to elicit skin irritation or sensitization (contact allergy).Made in the USA.

ZYMOX® Advanced Enzymatic Shampoo is formulated to soothe, hydrate, and relieve sensitive, extremely dry, itchy, or irritated skin of pets of any age with gentle, hypoallergenic and pH balanced ingredients.  Features the antimicrobial patented LP3 Enzyme System, a concentrated combination of naturally derived enzymes, plus hydrating Vitamin D3 and Avena sativa (oat) extract to calm, nourish, and care for the skin.  Does not contain parabens or detergents.Made in the USAUsesItchy allergy skinIrritated or Inflamed skinGentle cleansingHealthy skin supportFeaturesGentleSoothingNourishingNo sting, non-irritatingWon’t strip the coatTear-freePleasant smellingNo harsh ingredientsNo detergents, chlorines, or parabensSafe for all animalsAvailable Sizes: 12 oz and Gallon

ZYMOX® Equine Defense Advanced Formula Leave-On Conditioner is used to condition, soothe and moisturize dry, irritated skin, and detangle mane and tail. Formulated with the antimicrobial LP3 Enzyme System plus Vitamin D3 and oat extract to hydrate and provide a powerful protective skin layer. Hypoallergenic, pH balanced, and safe for horses and livestock of all ages. Free of parabens, and silicone to help keep the animal skin and coat healthy and shiny.Does not contain silicone or parabens.Made in the USA.UsesConditioning of skinIrritated skinPromotes skin healthFeaturesSoothingConditioningDetangling for the mane and tailMoisturizingPleasant smellingDries non-greasyLeave on or rinse offUse as a lotionNon-toxic, worry-free if lickedNo silicones or parabensNo steroidsTest cleanAvailable Sizes: 12 oz and GallonManage Conditions of the Hoof and HideThe ZYMOX Equine Defense products line utilizes the advanced technology of the patented LP3 Enzyme System for the management of chronic skin and hoof conditions. Containing no steroids, antibiotics, or petroleum by-products. These products are gentle and soothing to irritated skin, won’t harm surrounding healthy tissue, and don’t have the adverse effects associated with other conventional treatments.